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Strain Registration

Strain: STOCK.dmyTg(CMV-Mrs2)Kyo

Symbol: STOCK.dmyTg(CMV-Mrs2)Kyo
Strain: STOCK.dmyTg(CMV-Mrs2)
Substrain: Kyo
RGD ID: 11040939
Citation ID: RRID:RGD_11040939
Ontology ID: RS:0004131
Alleles: Mrs2
Also Known As: STOCK.dmyTg(CMV-Mrs2)/Kyo; NBRP Rat No: 0575; STOCK.dmyTg(CMV-Mrs2)Kyo
Type: transgenic
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: A transgene containing the CMV promoter and MRS2 gene was microinjected into the pronuclei of fertilized oocytes collected from Wistar rats. Transgenic offspring founder rats were backcrossed with WTC.DMy-dmy rats to obtain dmy/dmy homozygous and also hemizygous for the transgede (dmy/dmy, tg/+).
Coat Color: Albino
Inbred Generations: N2F13
Last Known Status: Cryopreserved Sperm






References

References - curated
# Reference Title Reference Citation
1. A rat mutation producing demyelination (dmy) maps to chromosome 17. Kuramoto T, etal., Mamm Genome 1996 Dec;7(12):890-4.
2. Immunohistochemical and morphometrical studies on myelin breakdown in the demyelination (dmy) mutant rat. Kuwamura M, etal., Brain Res. 2004 Oct 1;1022(1-2):110-6.
3. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Demyelination phenotype of the dmy rat is rescued. 1302502